CHELSEA HANDLER closed out her final show by thanking all the stars who showed up to celebrate with her.  And a message to her fans, quote, "I never really got a good chance to be serious and say 'thank you' and I want you to know that I am grateful for this career . . . I'll see you on Netflix." 


Sandra Bullock, Jennifer Aniston, and Mary McCormack also staged an "intervention" for Chelsea . . . Ellen DeGeneres did a shower scene with her . . . and DOZENS of other stars helped her sing a "We Are the World" parody song.  The "Goodbye to E!" song included Gwen Stefani, Miley Cyrus, Vanessa Hugdens, Dave Grohl, Trace Adkins, Alanis Morissette, Gerard Butler, Gwen Stefani, Fergie, Avril Lavigne, LeAnn Rimes, Tim Gunn, and Sammy Hagar.